3r77

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Template:STRUCTURE 3r77

Contents

Crystal structure of the D38A mutant of isochorismatase PhzD from Pseudomonas fluorescens 2-79 in complex with 2-amino-2-desoxyisochorismate ADIC

Template:ABSTRACT PUBMED 21454481

Function

[PHZD_PSEFL] Involved in the biosynthesis of the antibiotic, phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control.

About this Structure

3r77 is a 2 chain structure with sequence from Pseudomonas fluorescens. Full crystallographic information is available from OCA.

Reference

  • Li QA, Mavrodi DV, Thomashow LS, Roessle M, Blankenfeldt W. Ligand binding induces an ammonia channel in 2-amino-2-desoxyisochorismate (ADIC) synthase PhzE. J Biol Chem. 2011 Mar 29. PMID:21454481 doi:10.1074/jbc.M110.183418

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