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3s8r

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Template:STRUCTURE 3s8r

Contents

Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation

Template:ABSTRACT PUBMED 12680762

Function

[G7AC_PSEU7] Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).[1]

About this Structure

3s8r is a 2 chain structure with sequence from Pseudomonas. This structure supersedes the now removed PDB entry 1oqz. Full crystallographic information is available from OCA.

Reference

  • Kim JK, Yang IS, Rhee S, Dauter Z, Lee YS, Park SS, Kim KH. Crystal structures of glutaryl 7-aminocephalosporanic acid acylase: insight into autoproteolytic activation. Biochemistry. 2003 Apr 15;42(14):4084-93. PMID:12680762 doi:10.1021/bi027181x
  1. ↑ Matsuda A, Komatsu KI. Molecular cloning and structure of the gene for 7 beta-(4-carboxybutanamido)cephalosporanic acid acylase from a Pseudomonas strain. J Bacteriol. 1985 Sep;163(3):1222-8. PMID:2993240

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