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3std

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Template:STRUCTURE 3std

Contents

SCYTALONE DEHYDRATASE AND CYANOCINNOLINE INHIBITOR

Template:ABSTRACT PUBMED 9922139

Function

[SCYD_MAGGR] Catalyzes two steps in melanin biosynthesis. From scytalone they are two dehydration steps and one reduction step to yield melanin.

About this Structure

3std is a 3 chain structure with sequence from Magnaporthe grisea. Full crystallographic information is available from OCA.

Reference

  • Chen JM, Xu SL, Wawrzak Z, Basarab GS, Jordan DB. Structure-based design of potent inhibitors of scytalone dehydratase: displacement of a water molecule from the active site. Biochemistry. 1998 Dec 22;37(51):17735-44. PMID:9922139

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OCA

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