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2lsg
From Proteopedia
Contents |
Solution structure of the mouse Rev1 C-terminal domain
Template:ABSTRACT PUBMED 22700975
Function
[REV1_MOUSE] Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.[1]
About this Structure
2lsg is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.
Reference
- Wojtaszek J, Liu J, D'Souza S, Wang S, Xue Y, Walker GC, Zhou P. Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa. J Biol Chem. 2012 Jul 27;287(31):26400-8. doi: 10.1074/jbc.M112.380998. Epub 2012, Jun 14. PMID:22700975 doi:10.1074/jbc.M112.380998
- ↑ Masuda Y, Takahashi M, Fukuda S, Sumii M, Kamiya K. Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein. J Biol Chem. 2002 Jan 25;277(4):3040-6. Epub 2001 Nov 15. PMID:11711549 doi:10.1074/jbc.M110149200
