3hqh

From Proteopedia

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Template:STRUCTURE 3hqh

Contents 1 Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep1 2 Function 3 About this Structure 4 Reference

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep1

Template:ABSTRACT PUBMED 19818708

Function

[SPOP_XENTR] In complex with CUL3, involved in ubiquitination and proteasomal degradation of several substrates (By similarity).

About this Structure

3hqh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Zhuang M, Calabrese MF, Liu J, Waddell MB, Nourse A, Hammel M, Miller DJ, Walden H, Duda DM, Seyedin SN, Hoggard T, Harper JW, White KP, Schulman BA. Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell. 2009 Oct 9;36(1):39-50. PMID:19818708 doi:10.1016/j.molcel.2009.09.022