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3s5b

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Template:STRUCTURE 3s5b

Contents

Crystal Structure of CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans

Template:ABSTRACT PUBMED 22223640

Function

[NUCG_CAEEL] Endonuclease important for programmed cell death; it mediates apoptotic DNA fragmentation.

About this Structure

3s5b is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

  • Lin JL, Nakagawa A, Lin CL, Hsiao YY, Yang WZ, Wang YT, Doudeva LG, Skeen-Gaar RR, Xue D, Yuan HS. Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans. J Biol Chem. 2012 Mar 2;287(10):7110-20. Epub 2012 Jan 5. PMID:22223640 doi:10.1074/jbc.M111.316075

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OCA

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