4jy6

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Template:STRUCTURE 4jy6

Crystal structure of human Fab PGT123, a broadly reactive and potent HIV-1 neutralizing antibody

Template:ABSTRACT PUBMED 23658524

About this Structure

4jy6 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, Paulson JC, Sanders RW, Moore JP, Burton DR, Poignard P, Ward AB, Wilson IA. Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans. PLoS Pathog. 2013 May;9(5):e1003342. doi: 10.1371/journal.ppat.1003342. Epub 2013, May 2. PMID:23658524 doi:10.1371/journal.ppat.1003342

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