4hdd

From Proteopedia

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Template:STRUCTURE 4hdd

Contents 1 Domain swapping in the cytoplasmic domain of the Escherichia coli rhomboid protease 2 Function 3 About this Structure 4 Reference

Domain swapping in the cytoplasmic domain of the Escherichia coli rhomboid protease

Template:ABSTRACT PUBMED 23353827

Function

[GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.^{[1] [2]}

About this Structure

4hdd is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

• Lazareno-Saez C, Arutyunova E, Coquelle N, Lemieux MJ. Domain swapping in the cytoplasmic domain of the Escherichia coli rhomboid protease. J Mol Biol. 2013 Apr 12;425(7):1127-42. doi: 10.1016/j.jmb.2013.01.019. Epub 2013, Jan 23. PMID:23353827 doi:10.1016/j.jmb.2013.01.019

1. ↑ Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y. Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. Epub 2006 Nov 10. PMID:17099694 doi:10.1038/nsmb1179
2. ↑ Maegawa S, Ito K, Akiyama Y. Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane. Biochemistry. 2005 Oct 18;44(41):13543-52. PMID:16216077 doi:10.1021/bi051363k