2m02

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Template:STRUCTURE 2m02

Contents

3D structure of cap-gly domain of mammalian dynactin determined by magic angle spinning NMR spectroscopy

Template:ABSTRACT PUBMED 23648839

Function

[DCTN1_RAT] Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.

About this Structure

2m02 is a 1 chain structure with sequence from Rattus norvegicus. Full experimental information is available from OCA.

Reference

  • Yan S, Hou G, Schwieters CD, Ahmed S, Williams JC, Polenova T. Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End-Binding Protein EB1. J Mol Biol. 2013 May 4. pii: S0022-2836(13)00275-1. doi:, 10.1016/j.jmb.2013.04.027. PMID:23648839 doi:10.1016/j.jmb.2013.04.027

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