4jom

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Template:STRUCTURE 4jom

Contents

Structure of E. coli Pol III 3mPHP mutant

Template:ABSTRACT PUBMED 23672456

Function

[DPO3A_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

About this Structure

4jom is a 1 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  • Barros T, Guenther J, Kelch B, Anaya J, Prabhakar A, O'Donnell M, Kuriyan J, Lamers MH. A structural role for the PHP domain in E. coli DNA polymerase III. BMC Struct Biol. 2013 May 14;13:8. doi: 10.1186/1472-6807-13-8. PMID:23672456 doi:10.1186/1472-6807-13-8

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