4iqj

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Template:STRUCTURE 4iqj

Contents

Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome

Template:ABSTRACT PUBMED 23478062

Function

[DPO3A_THEAQ] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity).

About this Structure

4iqj is a 16 chain structure with sequence from Thermus aquaticus. Full crystallographic information is available from OCA.

Reference

  • Liu B, Lin J, Steitz TA. Structure of the PolIIIalpha-tauc-DNA complex suggests an atomic model of the replisome. Structure. 2013 Apr 2;21(4):658-64. doi: 10.1016/j.str.2013.02.002. Epub 2013 Mar, 7. PMID:23478062 doi:10.1016/j.str.2013.02.002

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OCA

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