3ef0

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Template:STRUCTURE 3ef0

Contents 1 The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase 2 Function 3 About this Structure 4 Reference

The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase

Template:ABSTRACT PUBMED 19026779

Function

[FCP1_SCHPO] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.

About this Structure

3ef0 is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

• Ghosh A, Shuman S, Lima CD. The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. Mol Cell. 2008 Nov 21;32(4):478-90. PMID:19026779 doi:10.1016/j.molcel.2008.09.021