4ht9

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Template:STRUCTURE 4ht9

Contents

Crystal structure of E coli Hfq bound to two RNAs

Template:ABSTRACT PUBMED 23605038

Function

[C6ECV6_ECOBD] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).[SAAS:SAAS005001_004_036087][HAMAP-Rule:MF_00436]

About this Structure

4ht9 is a 5 chain structure with sequence from Escherichia coli bl21(de3). Full crystallographic information is available from OCA.

Reference

  • Wang W, Wang L, Wu J, Gong Q, Shi Y. Hfq-bridged ternary complex is important for translation activation of rpoS by DsrA. Nucleic Acids Res. 2013 Jun 1;41(11):5938-48. doi: 10.1093/nar/gkt276. Epub 2013 , Apr 19. PMID:23605038 doi:10.1093/nar/gkt276

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OCA

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