3t6j

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Template:STRUCTURE 3t6j

Contents

Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 3.0 Angstroms

Template:ABSTRACT PUBMED 22493238

Function

[DPP3_HUMAN] Cleaves Arg-Arg-beta-naphthylamide.

About this Structure

3t6j is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bezerra GA, Dobrovetsky E, Viertlmayr R, Dong A, Binter A, Abramic M, Macheroux P, Dhe-Paganon S, Gruber K. Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6525-30. Epub 2012 Apr 9. PMID:22493238 doi:10.1073/pnas.1118005109

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OCA

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