1jbs

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 1jbs

Contents 1 Crystal structure of ribotoxin restrictocin and a 29-mer SRD RNA analog 2 Function 3 About this Structure 4 Reference

Crystal structure of ribotoxin restrictocin and a 29-mer SRD RNA analog

Template:ABSTRACT PUBMED 11685244

Function

[RNMG_ASPRE] This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity.

About this Structure

1jbs is a 4 chain structure with sequence from Aspergillus restrictus. Full crystallographic information is available from OCA.

Reference

• Yang X, Gerczei T, Glover LT, Correll CC. Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping. Nat Struct Biol. 2001 Nov;8(11):968-73. PMID:11685244 doi:10.1038/nsb1101-968