3tvl

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Template:STRUCTURE 3tvl

Contents

Complex between the human thiamine triphosphatase and triphosphate

Template:ABSTRACT PUBMED 23707715

Function

[THTPA_HUMAN] Hydrolase highly specific for thiamine triphosphate (ThTP).

About this Structure

3tvl is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Delvaux D, Kerff F, Murty MR, Lakaye B, Czerniecki J, Kohn G, Wins P, Herman R, Gabelica V, Heuze F, Tordoir X, Maree R, Matagne A, Charlier P, De Pauw E, Bettendorff L. Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase. Biochim Biophys Acta. 2013 May 22. pii: S0304-4165(13)00210-9. doi:, 10.1016/j.bbagen.2013.05.014. PMID:23707715 doi:10.1016/j.bbagen.2013.05.014

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OCA

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