4gh8

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Template:STRUCTURE 4gh8

Crystal structure of a 'humanized' E. coli dihydrofolate reductase

Function

[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

4gh8 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

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