3hps
From Proteopedia
Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)
Function
[LEU1_MYCTU] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity).
About this Structure
3hps is a 2 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.
Categories: 2-isopropylmalate synthase | Mycobacterium tuberculosis h37rv | Baker, E N. | Koon, N. | Squire, C J. | Amino-acid biosynthesis | Branched-chain amino acid biosynthesis | Enzyme | Leua | Leucine biosynthesis | Mycobacterium tuberculosis | Regulatory domain | Substrate | Tim barrel | Transferase
