2w44
From Proteopedia
Contents |
Structure DeltaA1-A4 insulin
Template:ABSTRACT PUBMED 20568733
Function
[A6XGL2_HUMAN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).[SAAS:SAAS022353_004_028339]
About this Structure
2w44 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Thorsoe KS, Schlein M, Steensgaard DB, Brandt J, Schluckebier G, Naver H. Kinetic evidence for the sequential association of insulin binding sites 1 and 2 to the insulin receptor and the influence of receptor isoform. Biochemistry. 2010 Jul 27;49(29):6234-46. PMID:20568733 doi:10.1021/bi1000118
