3pab

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Template:STRUCTURE 3pab

Contents

Crystal Structure of H2-Kb in complex with a mutant of the chicken ovalbumin epitope OVA-E1

Template:ABSTRACT PUBMED 22039305

Function

[HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system. [OVAL_CHICK] Non-inhibitory serpin. Storage protein of egg white.[1] [2] [B2MG_MOUSE] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.

About this Structure

3pab is a 6 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Denton AE, Wesselingh R, Gras S, Guillonneau C, Olson MR, Mintern JD, Zeng W, Jackson DC, Rossjohn J, Hodgkin PD, Doherty PC, Turner SJ. Affinity Thresholds for Naive CD8+ CTL Activation by Peptides and Engineered Influenza A Viruses. J Immunol. 2011 Oct 28. PMID:22039305 doi:10.4049/jimmunol.1003937
  1. ↑ Meek RL, Walsh KA, Palmiter RD. The signal sequence of ovalbumin is located near the NH2 terminus. J Biol Chem. 1982 Oct 25;257(20):12245-51. PMID:6749856
  2. ↑ Robinson A, Meredith C, Austen BM. Isolation and properties of the signal region from ovalbumin. FEBS Lett. 1986 Jul 28;203(2):243-6. PMID:3732511

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