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3rxx

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Template:STRUCTURE 3rxx

Contents

KPC-2 carbapenemase in complex with 3-NPBA

Template:ABSTRACT PUBMED 22330909

Function

[BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency.

About this Structure

3rxx is a 1 chain structure with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

Reference

  • Ke W, Bethel CR, Papp-Wallace KM, Pagadala SR, Nottingham M, Fernandez D, Buynak JD, Bonomo RA, van den Akker F. Crystal Structures of KPC-2 beta-Lactamase in Complex with 3-NPBA and PSR-3-226. Antimicrob Agents Chemother. 2012 Feb 13. PMID:22330909 doi:10.1128/AAC.06099-11

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OCA

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