1uvp

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spinqualitylabelsall models 1uvp, resolution 1.85Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

STRUCTURE OF THE COMPLEX OF PORCINE PANCREATIC ELASTASE IN COMPLEX WITH CADMIUM REFINED AT 1.85 A RESOLUTION (CRYSTAL B)

Overview

Two series of complete and highly redundant data sets were collected at, wavelengths of 1.00 and 2.00 Angstroms on a cadmium derivative of porcine, pancreatic elastase (PPE). Radiation damage to the sample was evaluated, qualitatively by inspecting consecutive difference electron density maps, during the course of the experiment. The nature of the radiation damage, was found to be identical at both wavelengths and was localized primarily, at the four disulfide bridges of PPE, the cadmium site and the two, methionine residues. For a quantitative examination of the radiation, damage, the decrease in the peak height of the cadmium ion in various, electron density maps was exploited. Again, no significant difference in, radiation damage between the two wavelengths was observed. This can be, ... [(full description)]

About this Structure

1UVP is a [Single protein] structure of sequence from [Sus scrofa] with CD, ACT, CL and GOL as [ligands]. Active as [Pancreatic elastase], with EC number [3.4.21.36]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

On the influence of the incident photon energy on the radiation damage in crystalline biological samples., Weiss MS, Panjikar S, Mueller-Dieckmann C, Tucker PA, J Synchrotron Radiat. 2005 May;12(Pt 3):304-9. Epub 2005 Apr 14. PMID:15840915

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