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4g59

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Template:STRUCTURE 4g59

Contents

Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma

Template:ABSTRACT PUBMED 23169621

Function

[RAE1C_MOUSE] Acts as a ligand for NKG2D.[1]

About this Structure

4g59 is a 4 chain structure with sequence from Murid herpesvirus 1 and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Wang R, Natarajan K, Revilleza MJ, Boyd LF, Zhi L, Zhao H, Robinson H, Margulies DH. Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion. Proc Natl Acad Sci U S A. 2012 Nov 19. PMID:23169621 doi:10.1073/pnas.1214088109
  1. ↑ Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity. 2000 Jun;12(6):721-7. PMID:10894171

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