This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4ej7
From Proteopedia
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, ATP-bound
Template:ABSTRACT PUBMED 23758273
About this Structure
4ej7 is a 3 chain structure with sequence from Acinetobacter baumannii aye. This structure supersedes the now removed PDB entry 3r78. Full crystallographic information is available from OCA.
Reference
- Stogios PJ, Spanogiannopoulos P, Evdokimova E, Egorova O, Shakya T, Todorovic N, Capretta A, Wright GD, Savchenko A. Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem J. 2013 Jun 12. PMID:23758273 doi:10.1042/BJ20130317
Categories: Acinetobacter baumannii aye | Kanamycin kinase | Anderson, W F. | CSGID, Center for Structural Genomics of Infectious Diseases. | Egorova, O. | Evdokimova, E. | Leo, R Di. | Minasov, G. | Savchenko, A. | Shakya, T. | Stogios, P J. | Tan, K. | Wright, G D. | Alpha/beta protein | Aminoglycoside phosphotransferase | Aminoglycoside | Antibiotic resistance | Center for structural genomics of infectious disease | Csgid | Eukaryotic protein kinase-like fold | Gtp | Intracellular | Kanamycin | National institute of allergy and infectious disease | Niaid | Phosphotransferase | Transferase
