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2huy

From Proteopedia

Revision as of 15:46, 21 February 2008 by OCA (Talk | contribs)
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Image:2huy.gif

2huy, resolution 1.700Å

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X-ray crystal structure of the complex between the Grb2-SH2 domain and a flexible ligand, fpYVN.

Disease

Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[100790], Haddad syndrome OMIM:[100790]

About this Structure

2HUY is a Single protein structure of sequence from Homo sapiens with and as ligands. Full crystallographic information is available from OCA.

Reference

Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:17001728

Page seeded by OCA on Thu Feb 21 17:46:06 2008

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