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3va3
From Proteopedia
Contents |
Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)
Template:ABSTRACT PUBMED 22718982
Function
[RNT_ECOLI] Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases.[HAMAP-Rule:MF_00157]
About this Structure
3va3 is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Hsiao YY, Duh Y, Chen YP, Wang YT, Yuan HS. How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes. Nucleic Acids Res. 2012 Jun 19. PMID:22718982 doi:10.1093/nar/gks548
