4k8z

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Template:STRUCTURE 4k8z

Contents

KOD Polymerase in binary complex with dsDNA

Template:ABSTRACT PUBMED 23733496

Function

[DPOL_PYRKO] Intein encoded endonucleases are thought to mediate intein mobility by site-specific recombination initiated by endonuclease cleavage at the "homing site" in gene that lack the intein. PI-PkoI recognizes 5'-GATTTAGATCCCTGTACC-3' and PI-PkoII recognizes 5'-CAGCTACTACGGTTAC-3'.

About this Structure

4k8z is a 3 chain structure with sequence from Thermococcus kodakarensis kod1. Full crystallographic information is available from OCA.

Reference

  • Bergen K, Betz K, Welte W, Diederichs K, Marx A. Structures of KOD and 9 degrees N DNA Polymerases Complexed with Primer Template Duplex. Chembiochem. 2013 Jun 17;14(9):1058-62. doi: 10.1002/cbic.201300175. Epub 2013, Jun 3. PMID:23733496 doi:10.1002/cbic.201300175

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