4kvq

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Template:STRUCTURE 4kvq

Contents

Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase wild type with palmitic acid bound

Template:ABSTRACT PUBMED 23757044

Function

[ALDEC_PROMM] Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane.[1]

About this Structure

4kvq is a 1 chain structure with sequence from Prochlorococcus marinus str. mit 9313. Full crystallographic information is available from OCA.

Reference

  • Khara B, Menon N, Levy C, Mansell D, Das D, Marsh EN, Leys D, Scrutton NS. Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase. Chembiochem. 2013 Jun 11. doi: 10.1002/cbic.201300307. PMID:23757044 doi:10.1002/cbic.201300307
  1. Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB. Microbial biosynthesis of alkanes. Science. 2010 Jul 30;329(5991):559-62. doi: 10.1126/science.1187936. PMID:20671186 doi:10.1126/science.1187936

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