CD59

CD59 (Cluster of Differentiation 59) is a protein which attaches to host cells via a GPI anchor. CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9. Mutations in CD59 causes disease involving thrombosis.

3D structures of CD59

Updated on 01-July-2013

1erg, 1erh, 1cdq, 1cdr, 1cds – hCD59 extracellular domain – human - NMR

2ofs, 2j8b, 2uwr, 2ux2 – hCD59 extracellular domain
1cds – hCD59 extracellular domain + intermedilysin