3ufc

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Template:STRUCTURE 3ufc

Contents

Characterization of a Cas6-related gene from Pyrococcus furiosus

Function

[CAS6L_PYRFU] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), also called psiRNA (prokaryotic silencing) in this organism (Potential).

About this Structure

3ufc is a 1 chain structure with sequence from Pyrococcus furiosus dsm 3638. Full crystallographic information is available from OCA.

Reference

  • Park HM, Shin M, Sun J, Kim GS, Lee YC, Park JH, Kim BY, Kim JS. Crystal structure of a Cas6 paralogous protein from Pyrococcus furiosus. Proteins. 2012 Jul;80(7):1895-900. doi: 10.1002/prot.24061. Epub 2012 Mar 23. PMID:22447673 doi:http://dx.doi.org/10.1002/prot.24061

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