1pyo

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Template:STRUCTURE 1pyo

Contents 1 Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho 2 Function 3 About this Structure 4 See Also 5 Reference

Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho

Template:ABSTRACT PUBMED 12920126

Function

[CASP2_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.

About this Structure

1pyo is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Caspase

Reference

• Schweizer A, Briand C, Grutter MG. Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway. J Biol Chem. 2003 Oct 24;278(43):42441-7. Epub 2003 Aug 14. PMID:12920126 doi:http://dx.doi.org/10.1074/jbc.M304895200