3rh1

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Template:STRUCTURE 3rh1

Contents

X-ray Structure of a cis-proline (P114) to alanine variant of Ribonuclease A

Template:ABSTRACT PUBMED 22273774

Function

[RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.[1]

About this Structure

3rh1 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  • Merlino A, Picone D, Ercole C, Balsamo A, Sica F. Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease. Biochimie. 2012 Jan 17. PMID:22273774 doi:10.1016/j.biochi.2012.01.010
  1. ↑ delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688

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