1mwa

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Template:STRUCTURE 1mwa

Contents 1 2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX 2 Function 3 About this Structure 4 See Also 5 Reference

2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX

Template:ABSTRACT PUBMED 11994422

Function

[B2MG_MOUSE] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system. [NDUA4_MOUSE] Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

About this Structure

1mwa is a 10 chain structure with sequence from Mus musculus. This structure supersedes the now removed PDB entry 1jtr. Full crystallographic information is available from OCA.

See Also

• Beta-2 microglobulin
• Major histocompatibility complex
• T-cell receptor

Reference

• Luz JG, Huang M, Garcia KC, Rudolph MG, Apostolopoulos V, Teyton L, Wilson IA. Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions. J Exp Med. 2002 May 6;195(9):1175-86. PMID:11994422