4fzx

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Template:STRUCTURE 4fzx

Contents

Exonuclease X in complex with 3' overhanging duplex DNA

Template:ABSTRACT PUBMED 23771145

Function

[EXOX_ECOLI] Capable of degrading both single-strand and double-strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA.

About this Structure

4fzx is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  • Wang T, Sun HL, Cheng F, Zhang XE, Bi L, Jiang T. Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease. Nucleic Acids Res. 2013 Jun 14. PMID:23771145 doi:10.1093/nar/gkt495

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OCA

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