4gnm

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Template:STRUCTURE 4gnm

Contents

Structure of rat cytosolic PEPCK Ld_2g in complex with oxalate and GTP

Template:ABSTRACT PUBMED 23127136

Function

[PCKGC_RAT] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

About this Structure

4gnm is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Johnson TA, Holyoak T. The Omega-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry. 2012 Nov 27;51(47):9547-59. doi: 10.1021/bi301278t. Epub 2012 Nov, 14. PMID:23127136 doi:10.1021/bi301278t

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