4b9m

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Template:STRUCTURE 4b9m

Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dA DNA lesion -thymine basepair in the post- insertion site.

Template:ABSTRACT PUBMED 23685671

About this Structure

4b9m is a 3 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

  • Gehrke TH, Lischke U, Gasteiger KL, Schneider S, Arnold S, Muller HC, Stephenson DS, Zipse H, Carell T. Unexpected non-Hoogsteen-based mutagenicity mechanism of FaPy-DNA lesions. Nat Chem Biol. 2013 May 19. doi: 10.1038/nchembio.1254. PMID:23685671 doi:10.1038/nchembio.1254

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OCA

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