Growth differentiation factor (GDF) are proteins which function in development.
- GDF-2 maintain the response of cholinergic neurons to acetylcholine.
- GDF-5 is expressed in the central nervous system and is involved in the development of joints and skeleton.
- GDF-8 or myostatin, controls the growth of muscle tissue. For more details see Group:MUZIC:Myostatin.
3D structures of growth differentiation factor
Updated on 08-July-2013
GDF-2
1zkz – hGDF – human
4fao – hGDF + serine/threonine-protein kinase receptor + activin receptor
GDF-5
2bhk, 1waq – hGDF
3evs – hGDF + bone morphogenetic receptor
3qb4 – hGDF (mutant) + bone morphogenetic receptor
GDF-8
3hh2 – mGDF + follistatin – mouse
3sek – mGDF + follistatin-related protein
