3tka

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Template:STRUCTURE 3tka

Contents 1 crystal structure and solution saxs of methyltransferase rsmh from E.coli 2 Function 3 About this Structure 4 Reference

crystal structure and solution saxs of methyltransferase rsmh from E.coli

Template:ABSTRACT PUBMED 22561317

Function

[RSMH_ECOLI] Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. In vitro, active on the assembled 30S subunit, but not naked 16S rRNA or 70S ribosomes.^{[1] [2]}

About this Structure

3tka is a 1 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

• Wei Y, Zhang H, Gao ZQ, Wang WJ, Shtykova EV, Xu JH, Liu QS, Dong YH. Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA. J Struct Biol. 2012 Apr 27. PMID:22561317 doi:10.1016/j.jsb.2012.04.011

1. ↑ Carrion M, Gomez MJ, Merchante-Schubert R, Dongarra S, Ayala JA. mraW, an essential gene at the dcw cluster of Escherichia coli codes for a cytoplasmic protein with methyltransferase activity. Biochimie. 1999 Aug-Sep;81(8-9):879-88. PMID:10572301
2. ↑ Kimura S, Suzuki T. Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA. Nucleic Acids Res. 2010 Mar;38(4):1341-52. doi: 10.1093/nar/gkp1073. Epub 2009, Dec 3. PMID:19965768 doi:10.1093/nar/gkp1073