1cwf

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Template:STRUCTURE 1cwf

Contents

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL CYCLOSPORIN

Template:ABSTRACT PUBMED 9769216

Function

[PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

About this Structure

1cwf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Kallen J, Mikol V, Taylor P, Walkinshaw MD. X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A. J Mol Biol. 1998 Oct 23;283(2):435-49. PMID:9769216

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