4jin

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Template:STRUCTURE 4jin

Contents

X-ray crystal structure of Archaeoglobus fulgidus Rio1 bound to (2E)-N-benzyl-2-cyano-3-(pyridine-4-yl)acrylamide (WP1086)

Template:ABSTRACT PUBMED 23523885

Function

[RIO1_ARCFU] Autophosphorylation of the rio1 protein is not necessary for maintenance of kinase activity. Prefers ATP over GTP. The yeast ortholog is involved in ribosome biogenesis.

About this Structure

4jin is a 1 chain structure with sequence from Archaeoglobus fulgidus dsm 4304. Full crystallographic information is available from OCA.

Reference

  • Mielecki M, Krawiec K, Kiburu I, Grzelak K, Zagorski W, Kierdaszuk B, Kowa K, Fokt I, Szymanski S, Swierk P, Szeja W, Priebe W, Lesyng B, Laronde-Leblanc N. Development of novel molecular probes of the Rio1 atypical protein kinase. Biochim Biophys Acta. 2013 Mar 20. pii: S1570-9639(13)00125-8. doi:, 10.1016/j.bbapap.2013.03.012. PMID:23523885 doi:10.1016/j.bbapap.2013.03.012

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