4k2p
From Proteopedia
The Structure of a Quintuple Mutant of the Tiam1 PH-CC-Ex Domain
Function
[TIAM1_HUMAN] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
About this Structure
4k2p is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
