4iru
From Proteopedia
Contents |
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Template:ABSTRACT PUBMED 23821544
Function
[RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
About this Structure
4iru is a 6 chain structure with sequence from Homo sapiens and Legionella pneumophila subsp. pneumophila str. philadelphia 1. Full crystallographic information is available from OCA.
Reference
- Mishra AK, Del Campo CM, Collins RE, Roy CR, Lambright DG. The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-Canonical Hydrolytic Mechanism. J Biol Chem. 2013 Jul 2. PMID:23821544 doi:10.1074/jbc.M113.470625
Categories: Homo sapiens | Legionella pneumophila subsp. pneumophila str. philadelphia 1 | Small monomeric GTPase | Collins, R E. | Delcampo, C M. | Lambright, D G. | Mishra, A K. | Roy, C R. | Arginine finger | Glutamate finger | Gtp hydrolysis | Gtp hydrolysis activator | Hydrolase-hydrolase complex | Intrinsic gtpase activity | Nucleotide binding | P-loop motif | Protein transport
