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1gw8

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Revision as of 11:02, 24 July 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 1gw8

Contents

quasi-atomic resolution model of bacteriophage PRD1 sus607 mutant, obtained by combined cryo-EM and X-ray crystallography.

Template:ABSTRACT PUBMED 12219080

Function

[CAPSD_BPPRD] Major capsid protein self-assembles to form an icosahedral capsid with a pseudo T=25 symmetry, about 66 nm in diameter, and consisting of 240 capsid proteins trimers. The capsid encapsulates an inner membrane and the genomic dsDNA genome. The major coat protein P3 and two assembly factors (P10 and P17) are needed during the assembly of the virus particle inside the host cell, when the capsid protein multimers are capable of enclosing the host-derived membrane, containing the virus-encoded membrane-associated proteins.

About this Structure

1gw8 is a 12 chain structure with sequence from Enterobacteria phage prd1. Full crystallographic information is available from OCA.

Reference

  • San Martin C, Huiskonen JT, Bamford JK, Butcher SJ, Fuller SD, Bamford DH, Burnett RM. Minor proteins, mobile arms and membrane-capsid interactions in the bacteriophage PRD1 capsid. Nat Struct Biol. 2002 Oct;9(10):756-63. PMID:12219080 doi:10.1038/nsb837

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OCA

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