4b6q

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Template:STRUCTURE 4b6q

Contents 1 Structure of Mycobacterium tuberculosis Type II Dehydroquinase inhibited by (2R)-2-(benzothiophen-5-yl)methyl-3-dehydroquinic acid 2 Function 3 About this Structure 4 See Also 5 Reference

Structure of Mycobacterium tuberculosis Type II Dehydroquinase inhibited by (2R)-2-(benzothiophen-5-yl)methyl-3-dehydroquinic acid

Template:ABSTRACT PUBMED 23198883

Function

[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]

About this Structure

4b6q is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

See Also

• Dehydroquinase

Reference

• Lence E, Tizon L, Otero JM, Peon A, Prazeres VF, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Gonzalez-Bello C. Mechanistic Basis of the Inhibition of Type II Dehydroquinase by (2S)- and (2R)-2-Benzyl-3-dehydroquinic Acids. ACS Chem Biol. 2012 Dec 6. PMID:23198883 doi:10.1021/cb300493s