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2m3s

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Revision as of 12:58, 24 July 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 2m3s

Contents

Calmodulin, i85l, f92e, h107i, l107i, a128t, m144r mutant

Template:ABSTRACT PUBMED 23630096

Function

[CALM_CHICK] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.

About this Structure

2m3s is a 1 chain structure with sequence from Gallus gallus. Full experimental information is available from OCA.

Reference

  • Moroz OV, Moroz YS, Wu Y, Olsen AB, Cheng H, Mack KL, McLaughlin JM, Raymond EA, Zhezherya K, Roder H, Korendovych IV. A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of nonnatural reaction. Angew Chem Int Ed Engl. 2013 Jun 10;52(24):6246-9. doi: 10.1002/anie.201302339., Epub 2013 Apr 29. PMID:23630096 doi:10.1002/anie.201302339

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OCA

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