4l77

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Template:STRUCTURE 4l77

Contents 1 P450cin Active Site Water: Implications for Substrate Binding and Solvent Accessibility 2 Function 3 About this Structure 4 Reference

P450cin Active Site Water: Implications for Substrate Binding and Solvent Accessibility

Template:ABSTRACT PUBMED 23829586

Function

[CINA_CITBR] Involved in the degradation of cineol (eucalyptol). Catalyzes the initial hydroxylation of cineole exclusively at the pro-R carbon to give the (S)-6beta-hydroxycineole. Cineole is the natural substrate of CinA.

About this Structure

4l77 is a 2 chain structure with sequence from Citrobacter braakii. Full crystallographic information is available from OCA.

Reference

• Madrona Y, Hollingsworth SA, Khan B, Poulos TL. P450cin Active Site Water: Implications for Substrate Binding and Solvent Accessibility. Biochemistry. 2013 Jul 18. PMID:23829586 doi:10.1021/bi4006946