3wcy
From Proteopedia
Murine Ifnar1 in complex with interferon-beta
Function
[INAR1_MOUSE] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. [IFNB_MOUSE] Has antiviral, antibacterial and anticancer activities.
About this Structure
3wcy is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
