4b1r

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Template:STRUCTURE 4b1r

Tetracycline repressor class D mutant H100A in complex with iso-7- Chlortetracycline

Function

[TETR4_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

About this Structure

4b1r is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

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