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3vos

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Template:STRUCTURE 3vos

Contents

Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With glycerol and sulfate From Mycobacterium tuberculosis H37Rv

Template:ABSTRACT PUBMED 22683789

Function

[DHAS_MYCTU] Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.[1]

About this Structure

3vos is a 1 chain structure with sequence from Mycobacterium tuberculosis. This structure supersedes the now removed PDB entries and 3kub. Full crystallographic information is available from OCA.

See Also

Reference

  • Vyas R, Tewari R, Weiss MS, Karthikeyan S. Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv. Acta Crystallogr D Biol Crystallogr. 2012 Jun;68(Pt 6):671-9. doi:, 10.1107/S0907444912007330. Epub 2012 May 17. PMID:22683789 doi:10.1107/S0907444912007330
  1. Shafiani S, Sharma P, Vohra RM, Tewari R. Cloning and characterization of aspartate-beta-semialdehyde dehydrogenase from Mycobacterium tuberculosis H37 Rv. J Appl Microbiol. 2005;98(4):832-8. PMID:15752328 doi:10.1111/j.1365-2672.2004.02505.x

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