3w01

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 3w01

Contents 1 Crystal structure of PcrB complexed with PEG from Staphylococcus aureus subsp. aureus Mu3 2 Function 3 About this Structure 4 Reference

Crystal structure of PcrB complexed with PEG from Staphylococcus aureus subsp. aureus Mu3

Template:ABSTRACT PUBMED 23322418

Function

[PCRB_STAA1] Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity).

About this Structure

3w01 is a 2 chain structure with sequence from Staphylococcus aureus subsp. aureus mu3. Full crystallographic information is available from OCA.

Reference

• Ren F, Feng X, Ko TP, Huang CH, Hu Y, Chan HC, Liu YL, Wang K, Chen CC, Pang X, He M, Li Y, Oldfield E, Guo RT. Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus. Chembiochem. 2013 Jan 21;14(2):195-9. doi: 10.1002/cbic.201200748. Epub 2013 Jan , 15. PMID:23322418 doi:10.1002/cbic.201200748